The killing of healthy ROS and creating unhealthy ROS reminds me of when people use scrubs, face brushes and/or harsh cleansers on their skin and get acne as a result: You scrub off the healthy, balanced oil that your skin produced. That means exfoliation, light and natural serums, and gentle cleansing. Mad Hippie Vitamin C Serum Review: A Natural Acne Fighting Solution. What is important to note is the term excess, and how this relates to vitamin C serums. The Journal of pathology, 229(2), 323-331. In addition, vitamin C serums seem to be more effective with the addition of vitamin E and ferulic acid. ‘Inhibitory effect of magnesium L-ascorbyl-2-phosphate (VC-PMG) on melanogenesis in vitro and in vivo’, Galadari, S., Rahman, A., Pallichankandy, S. & Thayyullathil, F (2017). This can cause problems for acne prone and sensitive skin. Fang, F. (2011). One research paper that I was to assess for the scholarship was the research of a MD/PhD student who was exploring reactive oxygen species (ROS) and how they are regulated by a certain protein. This can happen: Your vitamin C serum irritating skin and causing inflammation. However, this research is complex and is based on the observation that low levels of ROS may actually have protective effects, including antimicrobial activity. Vitamin C serum can and will act as a pro-oxidant, causing skin damage. Basically, you may be considering introducing a vitamin C serum into your skincare routine if: But is vitamin C serum good for acne-prone skin or does vitamin c serum cause acne? There is some evidence to suggest that using a vitamin C serum may make the skin more vulnerable to bacteria. They do not disrupt skin’s microbiome and do not interfere with ROS doing its job of keeping bacterial pathogens away. For example, multiple research studies have demonstrated that cancer cells have a greater level of ROS than normal cells – highlighting the role of ROS in tumor formation. Overall, though, there is not enough evidence to support the claims that vitamin C serums can cause acne. Choosing a selection results in a full page refresh. Even with extremely high doses of vitamin C, only a small amount will be available to the skin. By targeting inflammation, vitamin C may not prevent breakouts as there is no evidence to suggest that it reduces oil production or p-acnes proliferation. Does Vitamin C Serum Cause Acne Breakouts? Haywood, R., Wardman, P., Sanders, R. & Linge, C. (2003). Therefore, I look forward to such panels because I am able to read current research as it is developing, and often this is research I would never get the chance to explore on my own time. Sickness can include acne, dermatitis, folliculitis, and many others. Topical vitamin C formulations have also been shown to be as effective as topical hydroquinone therapy at reducing hyperpigmentation [3]. Concentrations of more than 20% offer no increase in effectiveness but may increase irritation and concentrations of less than 8% are too low to offer any significant antioxidant effects. I knew that it was because vitamin C serums broke the skin down because they discharged ROS due to their oxygenating effect in the skin. But keep eating them because of their vitamin content, low calories, fiber and other qualities that more likely contribute to longevity other than their antioxidant content. However, like anything, too much of something can be unhealthy. Though numerous foods and supplements contain vitamin C, keep in mind that skin care products formulated with this vitamin are more likely to aid … Cells in the body seem to require a specific balance of both antioxidants and ROS in order to function optimally. Beautycounter’s vitamin C serum is a blend of two ultra-stable forms of vitamin C. If you’re currently using a Vitamin C product, check to see what form of Vitamin C it contains. So if you used a vitamin C serum and it gave you acne, redness or any other skin issue, it is because the serum took away your body’s ability to fight off bacteria, and weakened it, … There is some evidence to suggest that using a vitamin C serum may make the skin more vulnerable to bacteria. ‘Reactive oxygen species and cancer paradox: To promote or to suppress?’. Too much ROS, of course, is a bad thing, as the scholarship applicant’s research (and many others) have supported, but the regulated amount of ROS naturally produced by the body is needed to prevent bacterial, fungal and other pathogenic invasion from infecting the body. It helps to repair your skin and it also supports tissue … Vitamin C works best at a concentration of 8-20%. For those of you looking to actively treat acne, look for vitamin C serums with sodium ascorbyl phosphate, as this was the form of vitamin C used in the research study mentioned earlier. The Mad Hippie Vitamin C Serum also contains the very effective vitamin C + vitamin E + ferulic acid combination at a fraction of the price of SkinCeuticals C E Ferulic. In theory, this would mean that ROS may actually help prevent acne by preventing the overgrowth of the p-acnes bacteria. Skin experts break down what the adverse reactions mean, and what you can do. Source: Zhang FQ, Wang YS, Lou ZP, JunDe Dong JD (2007). In vitamin C serums. Yes and no. When used consistently, vitamin C serums can make scars as a result of acne less pronounced. For example, multiple research studies have demonstrated that cancer cells have a greater level of ROS than normal cells – highlighting the role of ROS in tumor formation. ROS is needed for normal, healthy function, from cell proliferation to keeping bacterial pathogen away. There is also research that suggests that when antioxidants are in excess in the body, this contributes to virulence and oxidative stress. In fact, it may even help treat it faster! One that has long been hailed as a panacea of human disease and considered a hero of skin care: antioxidants. You want to help protect your skin against UV damage and enhance the protective effects of your sunscreen. Vitamin C Serum. This is due to the fact that vitamin C inhibits the main enzyme involved in the production of melanin, thereby decreasing melanin production [4]. You May Also Be Interested In: Dermalogica Biolumin-C Serum Review. As we mentioned in the introduction, ... As always, if you're using a topical treatment, such as a cream or a serum, it is important to perform a patch test before using it. However, one study found that the topical application of 5% sodium-L-ascorbyl-2-phosphate, a vitamin C derivative, over 12 weeks reduced the number of acne lesions in 61-71% of subjects (observer ratings vs subject ratings), One way of achieving this is to reduce the acidity of L-ascorbic acid to a pH of less than 3.5, Vitamin C works best at a concentration of 8-20%. He, W., Kim, H. K., Wamer, W. G., Melka, D., Callahan, J. H., & Yin, J. J. Skincare (like everything else in life) is NOT black and white. The cause of these breakouts are due to the fact that vitamin c brings dirt and oil that is in your skin’s pores to the surface, which can result in an acne breakout or two until the pores are completely cleared out. There is relatively little research specifically investigating the effect of topical vitamin C on acne. Then your body makes more oil in haste to replenish what was lost. ‘Antimicrobial actions of reactive oxygen species’. For example, a 5% concentration of a vitamin C derivative significantly improved the appearance of acne in the study mentioned earlier [11]. ‘Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage’. Their oxygenating effect creates ROS in the skin which breaks the skin down, creating inflammation, and leading increased susceptibility to pathogenic infection. Receive a complimentary Travel Set with your OUMERE purchase of $400 or more. Antioxidants & redox signaling, 20(6), 1000-1037. Fang, F. C. (2011). Redness is partially the result of inflammation. As one of the main causes of acne is inflammation, it is highly likely that vitamin C serums can help improve the appearance of acne. Planta (2010) 231: 461. https://doi.org/10.1007/s00425-009-1067-3. The Benefits Of Snail Mucin In Skin Care. This ROS-Antioxidant balance also has implications for acne-prone skin. American journal of clinical dermatology, 16(1), 27-33. In fact, a number of sunscreens are formulated with antioxidants for this exact reason. Vitamin C Serum Causes Me to Breakout Day by Day Beauty prides itself on having a Vitamin C Serum that is safe & effective for all skin types including sensitive skin. The oils and extracts themselves contribute to skin health because of their vitamin and mineral content, their fatty acid composition (for oils), and other factors that assist with maintaining the skin’s healthy balance. Does Yogurt Cause Acne? Try this serum as a spot treatment by applying it directly to post acne marks, allow the serum … ‘Topical vitamin C: A useful agent for treating photoaging and other dermatologic conditions’. As mentioned earlier, inflammation is one of the main causes of acne and causes the body to elicit an immune response. However, this research is very limited and it is not known whether the p-acnes bacteria is affected by ROS-antimicrobial activity (research seems to be focussed on the Salmonella enterica bacteria). Vitamin C’s role in collagen synthesis means that it also has a more general anti-aging effect as well. Vitamin C can be found in a number of foods you consume on a daily basis. Vitamin C sources There are a number of ways to get vitamin C to help clear-up and prevent the formation of cystic acne. However, this research is complex and is based on the observation that low levels of ROS may actually have protective effects, including antimicrobial activity. This means that instead of neutralizing free radicals, it will act as a free radical itself and begin to damage skin cells. All content, including, but not limited to, text, images, links, and other material does not constitute medical or other professional advice, and is not intended to be a substitute for professional medical advice. “Due to … (1996). Let’s explore the research behind vitamin C serums in order to answer these questions. Of the thousands and thousands of Vitamin C Serum bottles our company has sold, we have been contacted by a handful of customers that experienced breakouts when using the serum. Vitamin B12 has been implicated in its ability to cause acne when in excess in the body, however this has been noted for injections of the vitamin, and not when topically applied. The Best Mineral Sunscreens With Antioxidants, other antioxidant serums have more evidence to back up their anti-acne effects, https://www.ncbi.nlm.nih.gov/pubmed/14632206, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605218/#B3, https://www.ncbi.nlm.nih.gov/pubmed/15304189/, https://www.ncbi.nlm.nih.gov/pubmed/8543691/, https://www.sciencedirect.com/science/article/pii/S0891584917300035, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171981/, https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1524-4725.2005.31725, https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2133.1992.tb00122.x, https://www.ncbi.nlm.nih.gov/pubmed/9537007, https://onlinelibrary.wiley.com/doi/10.1111/jocd.12562, https://www.ncbi.nlm.nih.gov/pubmed/20367669. Some Vitamin C serums contain ingredients such as Ferulic acid to keep the Vitamin C stable for a longer period. Brescoll, J., & Daveluy, S. (2015). Unfortunately, even with the correct application, sunscreens can only block 55% of the free radicals produced by UV exposure [1]. When you use skin care formulated with beneficial oils and extracts, I do believe that there are benefits. Vitamin C products can certainly cause purging - this has happened to me with some vitamin C products as well, although not DE's Day Serum in particular. There are a number of different active forms of vitamin C but the most biologically active and well-studied is L-ascorbic acid. The vast majority of serums have a haphazard and dubious amount of the vitamin in the serum, formulated by no scientifically justifiable standards (the presence of vitamin C itself in a topical product to up-regulate collagen is not scientifically justified). Most people … Both mechanisms refer to vitamin C’s potent antioxidant effects. The rate of skin cell turnover is reduced causing a build-up of dead skin cells on the surface of the skin. A red flag for noticing if a product is actually irritating you and not just purging is if you're noticing pimples somewhere that you normally don't break out. It’s safe for most skin types. This means that you can eat all the blueberries you’d like, you are still going to age. For this reason, topical application of cosmetics containing vitamin C, such as vitamin C serums, are required to maintain sufficient skin levels of vitamin C, Topical vitamin C formulations have also been shown to be as effective as topical hydroquinone therapy at reducing hyperpigmentation. Redundant hydrogen peroxide scavengers contribute to Salmonella virulence and oxidative stress resistance. I use Cerave’s hydrating cleanser and the Hada Labo lotion. Vitamin C serums are not a product born of scientific research and rigorous methodology and experimentation. The rapid multiplication of the p-acnes bacteria causes an inflammatory response. Is vitamin C good for acne-prone skin? Laura is currently working in healthcare education and writes for ScienceBecomesHer in her spare time. This is because there is some evidence to suggest that ROS have antimicrobial effects, However, this research is very limited and it is not known whether the p-acnes bacteria is affected by ROS-antimicrobial activity (research seems to be focussed on the, Plenty of research has demonstrated that Vitamin C has potent anti-inflammatory effects, There is relatively little research specifically investigating the effect of topical vitamin C on acne. The paper focused on how alterations in this protein can affect how much ROS is produced by the body, and when unregulated can lead to certain types of cancer. Woolery-Lloyd, H., Baumann, L. & Ikeno, H. (2010). However, it appears that ROS at high levels can have tumor-suppressing effects and can destroy cancer cells and antioxidants impede this process, This ROS-Antioxidant balance also has implications for acne-prone skin. So now it seems, from an oxidation standpoint, vitamin C serums damage the skin in two ways: The two together creates a storm that disrupts the body’s ability to maintain a healthy balance which is why vitamin C serums have destroyed so many people’s skin. Most on the market contain the L-ascorbic form, which turns brown. Notify me of follow-up comments by email. Vitamin C serums are one of those fad products that I hope will disappear with time, and I am certain that we will see adult acne disappear with it too. When too much ROS is produced, disease can occur. Darr, D., Combs, S., Dunston, S., Manning, T. & Pinnell, S. (1992). The ideal vitamin C serum would contain L-ascorbic acid, have a concentration of 8-20%, and a pH of less than 3.5. I know this cause I made such serum, like above 20% of net weight, when I applied it upon my facial skin, the little tiny acne popped up in just one night, I wondered why, apparently that's cause of the vitamin c powder I dilluted in the serum mix. Concentrations of more than 20% offer no increase in effectiveness but may increase irritation and concentrations of less than 8% are too low to offer any significant antioxidant effects. Evidence of topical vitamin C’s anti-inflammatory effects can be seen from its ability to reduce erythema caused by inflammation after sun exposure [8], and following laser resurfacing [9]. Last week I had the honor of sitting on a scholarship panel for the University of California, Irvine medical school. One way of achieving this is to reduce the acidity of L-ascorbic acid to a pH of less than 3.5 [2]. ‘Sunscreens inadequately protect against ultraviolet-A-induced free radicals in skin: implications for skin aging and melanoma?’. The authors of the aforementioned study identify two different mechanisms by which vitamin C may exert its effects on acne. Scales, B. S., & Huffnagle, G. B. However, the scale can tip the other way and when there are not enough ROS in the body, disease can also occur. Reactive oxygen species have a necessary function in the body that I was previously unaware of: they act as a natural anti-microbial agent. Unfortunately, even with the correct application, sunscreens can only block 55% of the free radicals produced by UV exposure, Even with extremely high doses of vitamin C, only a small amount will be available to the skin. The microbiome in wound repair and tissue fibrosis. It is unlikely that vitamin C serums will cause acne. (2004). The skin becomes stripped and imbalanced. This means that it needs to be formulated in a way that provides stability and permeability. Individuals with acne have a higher concentration of skin surface lipids that when oxidized are highly comedogenic and antioxidants may prevent this oxidizing effect, thereby preventing comedogenesis. (2013). Vitamin C is anti-inflammatory, and a vitamin C serum can both help clear up acne and reduce the redness associated with it—as well as improve skin texture. Vitamin C For Acne. This means that when there is an overproduction of oil the p-acnes bacteria are able to rapidly multiply. When antioxidants are in oils and extracts, they are diluted and in low concentrations. Since antioxidants, such as vitamin C, neutralize ROS, they may inhibit these protective effects and could cause an increase in the p-acnes bacteria. Here’s why Vitamin D supplements can cause acne: the first key reason is that Vitamin D stimulates testosterone, which is the primary hormone that aggravates hormonal acne. However, some research suggests that small amounts of free radicals are good for us. Plenty of research has demonstrated that Vitamin C has potent anti-inflammatory effects [7]. I believe in tried and true methodology and taking a scientific, modern take on long-held skin care practices. Collagen production decreases as we naturally age and the rate at which it decreases is drastically enhanced when the skin experiences large and cumulative amounts of UV exposure. This website is intended for informational and/or educational purposes only. This is something I have done for two years, and it is an excellent opportunity, not just to provide funding for great research, but to learn of what new biological research is being conducted. The ability of topical vitamin C to reduce inflammation and erythema suggests that it would help improve the appearance of acne. The breakouts can happen due to the base of the Vitamin C serum. However, lower concentrations may be effective for inflammatory skin conditions such as acne [2]. I don't have marks that are skin deep and cause pits on my skin * Touchwood * However, they are visible on the skin as brown spots. The dead skin cells block the hair follicle and trap the oil inside. And there is enough evidence to the contrary to support that the free radical theory is possibly an overgeneralization of how aging actually occurs, and that the aging process is much more complex than just: accumulation of ROS over time —> aging. Science can’t explain why. Vitamin C Serum is one of the most effective serums on the market because they provide several skin benefits that including treating acne and reducing acne scars. Vitamin C is the most abundant antioxidant in the skin and is essential for the production of collagen. Or does vitamin C serum cause acne? Farris, P. (2006). When I wrote some time ago about how damaging vitamin C serums are to the skin, I received a mountain of responses of women and men telling me their stories of how vitamin C serums gave them acne and other skin diseases. Vitamin C Serum for Acne Scars (Hyperpigmentation) Recent studies have demonstrated that the use of vitamin C as a topical treatment can reduce the appearance of acne scars. Antimicrobial actions of reactive oxygen species. Are you looking to incorporate a vitamin C serum into your skincare routine but worried that it will break you out? In this case, they assist with anti-inflammatory action and have skin health benefits. Journal of bacteriology, 191(14), 4605-4614. It turns out that it may not be as simple as ROS = bad, Antioxidants = good. Too much ROS can lead to cell death and tumor formation. The microbiome can get disrupted by raising skin’s pH (through use of foaming and/or alkaline cleansers), by introducing an inflammatory agent to the skin (essential oils or fragrance), by mechanically damaging the skin (such as with a scrub, microdermabrasion, dermarolling, etc), all of which is well known. And yet, many of my clients with oily, acne-prone skin complain their acne got worse after introducing a Vitamin C serum into their skincare routine. Maybe not now, but certainly over time. You can also obtain vitamin C through a supplement. Vitamin C serums are acidic, which means they slough away dead cells from the skins surface leaving it brighter and smoother. Vitamin C is generally safe to use, but those with sensitive skin should take into account the pH level of their vitamin C products, particularly if it includes vitamin C in the form of LAA. Espinal-Perez, L., Moncada, B. The 5-Step Glossier Skincare Regimen For Acne-Prone Skin | Pinkermann. She has experience in plastic and reconstructive surgery, dermatology, and aesthetics and has received training in laser treatments. OUMERE Skin Care is not intended to diagnose, cure or treat any ailment. Niacinamide and Hyaluronic Acid Together = Super Skin Hydration. This means that topical antioxidants should be used in addition to sunscreens to provide protection against free radical damage. Galadari, S., Rahman, A., Pallichankandy, S., & Thayyullathil, F. (2017). Vitamin C serums are a product born of clever marketing, the misrepresentation of results, and profitable conflicts of interest. ... the higher likelihood it may cause a problem for those with extremely problematic skin like myself. One cause of acne breakouts is free radicals because they are known to cause skin inflammation which traps dirt and bacteria in pores and cause acne to occur. A review of vitamin B12 in dermatology. Lumene Bright Now Vitamin C Dry Skin Cocktail. Alster, T. & West, T. (1998). Your email address will not be published. However, what I didn’t know at the time was how antioxidants, when in concentrated form can take away beneficial ROS, leading to bacterial infection. In addition to brightening your complexion, it gently exfoliates and sloughs off dead skin without causing irritation. Can you recommend some good Vitamin C serums for fading acne marks? However, one study found that the topical application of 5% sodium-L-ascorbyl-2-phosphate, a vitamin C derivative, over 12 weeks reduced the number of acne lesions in 61-71% of subjects (observer ratings vs subject ratings) [11]. If this were true, then a potent antioxidant serum, such as a vitamin C serum, may actually make acne worse by neutralizing the ROS that are keeping the p-acnes bacteria under control. Dinakar, C., Abhaypratap, V., Yearla, S.R. This means that it can help prevent premature aging and skin cancers that are due to sun exposure (photoaging). Their antioxidant effect destroys the healthy ROS created by the body to prevent bacterial infection. For this reason, topical application of cosmetics containing vitamin C, such as vitamin C serums, are required to maintain sufficient skin levels of vitamin C [2]. However, I believe we should consider adding one more to the list of skin damaging agents. Hébrard, M., Viala, J. P., Méresse, S., Barras, F., & Aussel, L. (2009). Furthermore, higher antioxidant levels in cells are associated with lower ROS levels. The addition of ferulic acid to L-ascorbic acid improves the stability of the vitamin C serum and reduces the acidity to a pH of below 3.5. But this time the oil is inflammatory, and your skin has all the hallmarks of acne: redness, closed comedones etc. It is a bottle whose exterior is cloaked in the trustworthy guise of science, and its contents a nostrum potion. Skin-Care Tips Keep in mind, if you have acne, applying Vitamin C to active breakouts can cause irritation. et al. Chemosphere 67:44–50. This vitamin C serum is a cult-favorite for good reason. So far, so good. Zhang FQ, Wang YS, Lou ZP, JunDe Dong JD (2007) Effect of heavy metal stress on antioxidative enzymes and lipid peroxidation in leaves and roots of two mangrove plant seedlings (Kandelia candel and Bruguiera gymnorrhiza). Vitamin C has an excellent safety profile. What Should I Look For In A Vitamin C Serum? In addition, common antibiotic treatments for acne, such as tetracycline, doxycycline, and erythromycin have demonstrated antioxidant effects by reducing ROS. This kind of free radical is … Vitamin A does not cause acne, but too much of it actually can worsen some conditions. Furthermore, if ROS were found to have antimicrobial effects on the p-acnes bacteria, it is not known what amount of antioxidant would unbalance the ROS-Antioxidant equilibrium in order to affect this. Too much vitamin C actually causes acne flare-ups especially on serums. $80 at Sephora So do antioxidants in skin care actually have any benefit? & Castanedo-Cazares, J. These changes result in the destruction of collagen and elastin and can potentially cause skin cancer. When are antioxidants in concentrated form? In addition, vitamin C can improve facial erythema which is often a concern in acne and post inflammatory erythema. And this is important in the context of skin care. Paiva, C. N., & Bozza, M. T. (2014). Vitamin C for Acne: Why Vitamin C for Skin? Many will ask, is Vitamin C serum good for acne, the answer to which is, well, it depends. When that balance gets disrupted, the skin gets sick. Acne Diet Myths & Facts. This is because there is some evidence to suggest that ROS have antimicrobial effects [6]. It is caused by multiple overlapping factors: One of the ways we can work out whether vitamin C is good for acne-prone skin or whether vitamin C serum causes acne is to look at how vitamin C affects oil production, skin cell turnover, p-acnes bacteria, and inflammation. However, lower concentrations may be effective for inflammatory skin conditions such as acne. No good tho. In fact, this topical vitamin C formulation was the first to be clinically proven. According to the U.S. National Library of Medicine, "many people over age 50 lose the ability to absorb vitamin B12 from foods," and weight-loss surgery can cause the same problem. So if you used a vitamin C serum and it gave you acne, redness or any other skin issue, it is because the serum took away your body’s ability to fight off bacteria, and weakened it, inviting pathogens to infect your skin. ( 2003 ) acne lesions after 6 weeks of daily use to … Hippie. 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